Norfentanyl

Confirming fentanyl exposure relies on norfentanyl, the primary inactive metabolite of fentanyl formed through N-dealkylation by CYP3A4 and the principal urinary marker for this potent synthetic opioid. Laboratory testing applications include pain management compliance monitoring, forensic toxicology investigations of fentanyl-related overdose deaths, postmortem toxicology, workplace drug testing programs that include synthetic opioids, and clinical toxicology assessments in emergency departments evaluating suspected opioid toxicity. UTAK’s Pain Management and Pain Management Plus panels contain norfentanyl in lyophilized urine and whole blood matrices at multiple concentration levels, supporting both immunoassay screening and confirmation methods used in clinical and forensic laboratories. Stock and custom QC solutions can incorporate fentanyl and related opioids such as morphine, hydrocodone, hydromorphone, oxycodone, oxymorphone, methadone, buprenorphine, and other pain management analytes to address your laboratory’s comprehensive synthetic opioid and drugs of abuse testing requirements.